Anastasia Pavlyuchenkova was beaten in the second round of the Topshelf Open on Thursday as the sixth seed crashed out at the hands of home favourite Kiki Bertens.
Pavlyuchenkova cruised past American qualifier Maria Sanchez in her opener but was comfortably dispatched by Bertens - going down 6-2 6-2.
Bertens - ranked 132nd in the world - saved all five break-points in the 74-minute encounter as she repeated last year's French Open victory on the grass in the Netherlands.
She will face defending champion Coco Vandeweghe in the last eight.
Second seed Jelena Jankovic endured no such problems as she breezed past Czech qualifier Andrea Hlavackova 6-1 6-4.
Jankovic has reached the quarter-finals of a tournament just twice in 2015 but was rarely troubled as she set up a last-eight meeting with Annika Beck.
Beck's 6-4 6-4 success represents her first victory over Klara Koukalova in five attempts, with the Czech giving her opponent a helping hand courtesy of seven double-faults.
The first set saw the pair manage just one hold between them with Koukalova broken on all but three service games in the match.
The make-up of the remaining quarter-final was also decided on Thursday as fourth seed Belinda Bencic booked a meeting with Kristina Mladenovic.
Swiss Bencic needed just 74 minutes to get past recent French Open quarter-finalist Alison van Uytanck 6-3 6-2.